Showing posts with label YouTube. Show all posts
Showing posts with label YouTube. Show all posts
Friday, November 19, 2021
Thursday, November 18, 2021
Wednesday, November 17, 2021
Thursday, November 11, 2021
November 11
America Has Lost the Plot on COVID We’re avoiding the hardest questions about living with the coronavirus long term. ........ We know how this ends: The coronavirus becomes endemic, and we live with it forever. ........ How do we manage the transition to endemicity? When are restrictions lifted? And what long-term measures do we keep, if any, when we reach endemicity? ......
How to Survive for Three Days in the Wilderness This 72-hour plan will buy you enough time to wait for search and rescue to arrive.
The answers were simpler when we thought we could vaccinate our way to herd immunity.
....... The Delta variant and waning immunity against transmission mean herd immunity may well be impossible even if every single American gets a shot. ....... The path ahead is not just unclear; it’s nonexistent. We are meandering around the woods because we don’t know where to go. ......... Even when we reach endemicity—when nearly everyone has baseline immunity from either infection or vaccination—the U.S. could be facing tens of millions of infections from the coronavirus every year, thanks to waning immunity and viral evolution. (For context, the flu, which is also endemic, sickens roughly 10 to 40 million Americans a year.) ......... COVID-19 policies differ wildly by state, county, university, workplace, and school district. And because of polarization, they have also settled into the most illogical pattern possible: The least vaccinated communities have some of the laxest restrictions, while highly vaccinated communities—which is to say those most protected from COVID-19—tend to have some of the most aggressive measures aimed at driving down cases. ........ We don’t know how much immunity may continue to wane, how long the effects of a booster last, the exact incidence of long COVID in the vaccinated, or if a new variant will upend even the best-laid plans. .......... One plausible goal is to focus on minimizing COVID-19’s impact on hospitals. A collapsed health-care system means more people will die, not just of COVID-19 but from other treatable diseases and injuries. ........... By the time hospitalizations start to rise, a bigger increase may already be baked in with people already infected but not yet sick enough to see a doctor. ......... COVID shots for kids 5 to 11 were authorized last week, and data for those ages 2 to 4 are expected before the end of the year. ........ Vaccinated parents, living with vaccinated children, who have vaccinated grandparents, can worry that much less about the virus’s worst impacts, and start behaving less cautiously. ..........The risk of hospitalization for an unvaccinated person over 80 is 25 times that for an unvaccinated person under 18.
...... two communities with 90 versus 99 percent of the elderly vaccinated actually have a tenfold difference in the number of people at risk for hospitalization. ......... Even when the coronavirus is endemic, it will still make people sick and it will still cause deaths and hospitalizations. That means our fight against COVID-19 is not over, and we might consider strategies sustainable over the long term. Better ventilation, for example, can make indoor spaces safer against all respiratory viruses, not just COVID-19. And even without mask mandates, people who feel at risk can still voluntarily mask up. In the longer term, Çevik says, we also need less focus on policies that work by “reducing small risks among many” and more on policies targeted at the people most affected by COVID-19. During the pandemic, the virus has disproportionately sickened people who are poor, who are less likely to be able to work from home, and who are less likely to have space to isolate from their family at home. When COVID-19 becomes endemic, it will likely, as many diseases are, continue to be correlated with poverty.How to Survive for Three Days in the Wilderness This 72-hour plan will buy you enough time to wait for search and rescue to arrive.
Monday, November 08, 2021
News: November 8
Alphabet Chases Wonder Drugs With DeepMind AI Spinoff Isomorphic Labs Predicting the structure of proteins, the complex molecules underpinning all biology, is notoriously difficult. But DeepMind’s AlphaFold2 made a quantum leap in capability, producing results that matched experimental data down to a resolution of a few atoms. ........ In July, the company published a paper describing AlphaFold2, open-sourced the code, and dropped a library of 350,000 protein structures with a promise to add 100 million more. ......... There have been three AI drug discovery IPOs in the last year, and mature startups—including Exscientia, Insilico Medicine, Insitro, Atomwise, and Valo Health—have earned hundreds of millions in funding. Companies like Genentech, Pfizer, and Merck are likewise working to embed AI in their processes. ........ “Biology is likely far too complex and messy to ever be encapsulated as a simple set of neat mathematical equations,” Hassabis wrote in his recent blog post.
Protein Folding AI Is Making a ‘Once in a Generation’ Advance in Biology Proteins are the minions of life. They form our bodies, fuel our metabolism, and are the target of most of today’s medicine. ......... Similar to Transformers, many protein units further assemble into massive, moving complexes that change their structure depending on their functional needs at the moment. ......... One of biology’s grandest challenges for the past 50 years has been deciphering how a simple one-dimensional ribbon-like structure turns into 3D shapes, equipped with canyons, ridges, valleys, and caves. ........ Deciphering protein folding is bound to illuminate an entire new landscape of biology we haven’t been able to study or manipulate. The fast and furious development of Covid-19 vaccines relied on scientists parsing multiple protein targets on the virus, including the spike proteins that vaccines target. Many proteins that lead to cancer have so far been out of the reach of drugs because their structure is hard to pin down.
In Glasgow, I saw three big shifts in the climate conversation A lot has changed in the past six years. ...... The climate conversation has shifted dramatically, and for the better. ....... accomplishing that will require a green Industrial Revolution in which we decarbonize virtually the entire physical economy: how we make things, generate electricity, move around, grow food, and cool and heat buildings ........
Why scaling innovation is key to stopping climate change Before the last major COP meeting, innovation was barely on the climate agenda. This year it will take center stage. ..........
My message to the world at COP26 We need to make zero-carbon alternatives affordable for people all over the world......... It’s deeply unfair that the world’s poorest people, who contribute the least to climate change, will suffer from its effects the most. Rich and middle-income countries are causing the vast majority of climate change, and we need to be the ones to step up and invest more in adaptation. ....... People are already being affected by a warmer planet. Those impacts will only get worse, especially for the world’s poorest. .........
“But just as mathematics turned out to be the right description language for physics, biology may turn out to be the perfect type of regime for the application of AI.”
Protein Folding AI Is Making a ‘Once in a Generation’ Advance in Biology Proteins are the minions of life. They form our bodies, fuel our metabolism, and are the target of most of today’s medicine. ......... Similar to Transformers, many protein units further assemble into massive, moving complexes that change their structure depending on their functional needs at the moment. ......... One of biology’s grandest challenges for the past 50 years has been deciphering how a simple one-dimensional ribbon-like structure turns into 3D shapes, equipped with canyons, ridges, valleys, and caves. ........ Deciphering protein folding is bound to illuminate an entire new landscape of biology we haven’t been able to study or manipulate. The fast and furious development of Covid-19 vaccines relied on scientists parsing multiple protein targets on the virus, including the spike proteins that vaccines target. Many proteins that lead to cancer have so far been out of the reach of drugs because their structure is hard to pin down.
In Glasgow, I saw three big shifts in the climate conversation A lot has changed in the past six years. ...... The climate conversation has shifted dramatically, and for the better. ....... accomplishing that will require a green Industrial Revolution in which we decarbonize virtually the entire physical economy: how we make things, generate electricity, move around, grow food, and cool and heat buildings ........
we need a huge number of new inventions
.......... (It made me wish we could get the same kind of turnout and excitement for conferences on global health!)Why scaling innovation is key to stopping climate change Before the last major COP meeting, innovation was barely on the climate agenda. This year it will take center stage. ..........
innovation is the only way the world can cut greenhouse gas emissions from roughly 51bn tonnes per year to zero by 2050.
.......... sustainable airplane fuel,green steel
and extra-powerful batteries—now exist and are ready to scale. ........... Once you can make green hydrogen in a lab, you have to prove that that it works—safely and reliably—at scale. That means building an enormous physical plant, ironing out engineering, supply chain and distribution issues, repeating them over and over again and steadily cutting costs. Demonstration projects like this are hugely complicated, extremely risky, and extraordinarily expensive—and it’s very hard to finance them. ......... At COP, the world should put scaling clean technology innovation—both for mitigating the worst impacts of climate and for adapting to the impacts that we will already feel—on the agenda in the same way it put R&D on it in 2015.My message to the world at COP26 We need to make zero-carbon alternatives affordable for people all over the world......... It’s deeply unfair that the world’s poorest people, who contribute the least to climate change, will suffer from its effects the most. Rich and middle-income countries are causing the vast majority of climate change, and we need to be the ones to step up and invest more in adaptation. ....... People are already being affected by a warmer planet. Those impacts will only get worse, especially for the world’s poorest. .........
Sunday, November 07, 2021
Saturday, November 06, 2021
November 6
You can cut all the flowers but you can not keep spring from coming.
— Prabhakar Bagchand (@PBagchand) November 6, 2021
- Pablo Neruda pic.twitter.com/Jjk1RUj0C7
हाम्रो परिवारमा भाइटीका ! सबै दिदीबहिनी दाज्यूभाइहरूको भलो होस्!! pic.twitter.com/7rjTppbnR6
— Baburam Bhattarai (@brb1954) November 6, 2021
'Osh' शीत (Dew) - Our busy and confined urban life in concrete jungle will not rejoice the essence of 'Osh'. This can only be witnessed where nature has no concrete encroachment. In village when I woke up in morning, I walked barefoot on wet grass. It was great feeling of peace pic.twitter.com/czFmeviccO
— Chandrakishore चन्द्रकिशोर (@Kishore_chandra) November 6, 2021
देश तथा विदेशमा रहनु भएका सम्पुर्ण दाजुभाइ तथा दिदी बहिनीहरुमा भाइटिका, भरदूतिया, भाईदूज को हार्दिक मंगलमय शुभकामना!#भाईदूज #भाइटिका pic.twitter.com/D3ZGLGEx3N
— Lal Kishor Sah (@_LalKishorSah) November 6, 2021
भाइटिकाको उपलक्ष्यमा सबै दिदीबहिनीहरूको सुख, समृद्धि र सुस्वास्थ्यको हार्दिक शुभकामना
— Jugal Bhurtel (@JugalBhurtel) November 6, 2021
🙏🙏🙏 pic.twitter.com/ttTeZYd0ro
आज उहाँहरू बिहानै देखि सरसफाईमा जुट्नुभएको रहेछ ! #भाइटिका तयारी #तिहार चिटिक्क pic.twitter.com/H0uV7Fyitq
— Manushi Yami Bhattarai (@manushiyb) November 6, 2021
बिष्णुजी, म तपाईसङ माफी माग्न चाहन्छु। साथै, म तपाईंलाई ढुक्क हुन अनुरोध गर्छु कि वैकल्पिक राजनीतिलाई गलत दिशामा जान दिनेछैनौं। एकाध व्यक्तिको राप्रपाकरणले समग्र वैकल्पिक राजनीतिको आन्दोलन कमजोर हुँदैन।
— Milan Pandey (@MilanPandey) November 6, 2021
***https://t.co/K1EZQf4k2b
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